A biomimetic transformation of serratinine into serratezomine A through a modified Polonovski reaction.
نویسندگان
چکیده
Application of a modified Polonovski reaction for serratinine (1) resulted in generation of serratezomine A (2) with a novel seco-serratinine-type skeleton recently isolated from the club moss Lycopodium serratum var. serratum. This biomimetic transformation supports a biogenetic pathway proposed for serratezomine A (2). The absolute stereochemistry of serratezomine A (2) was established by an induced exciton chirality and modified Mosher methods.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 67 15 شماره
صفحات -
تاریخ انتشار 2002